ELISA EDEM2 anti-
Quantity :50µg
Clone Number:
Aliases:bA4204.1 antibody; C20orf31 antibody; C20orf49 antibody; EDEM 2 antibody; EDEM2 antibody; EDEM2_ antibody; ER degradation enhancer mannosidase alpha like 2 antibody; ER degradation enhancing alpha mannosidase like 2 antibody; ER degradation enhancing alpha mannosidase like protein 2 antibody; ER degradation enhancing mannosidase like protein 2 antibody; ER degradation-enhancing alpha-mannosidase-like 2 antibody; FLJ10783 antibody; UNQ573/PRO1135 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q9BV94
Immunogen:Recombinant ER degradation-enhancing alpha-mannosidase-like protein 2 protein (22-300AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Background:Initiates the endoplasmic reticµLum-associated degradation (ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2 (PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:Non-conjµgated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:EDEM2
Research Areas:Signal transduction