ELISA DRG1 anti-

Quantity :50µL Clone Number: Aliases:Developmentally regµLated GTP binding protein 1 antibody; Developmentally-regµLated GTP-binding protein 1 antibody; DKFZp434N1827 antibody; DRG 1 antibody; DRG-1 antibody; DRG1 antibody; DRG1_ antibody; NEDD 3 antibody; NEDD-3 antibody; NEDD3 antibody; Neural precursor cell expressed developmentally down regµLated protein 3 antibody; Neural precursor cell expressed developmentally down-regµLated protein 3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9Y295 Immunogen:Fusion protein of DRG1 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 Background:DRG1 (developmentally regµLated GTP binding protein 1), also known as NEDD3 (neural precursor cell expressed developmentally down-regµLated protein 3), is a 367 amino acid protein that localizes to the cytoplasm and belongs to the GTP1/OBG family. Expressed at high levels in heart, kidney and skeletal muscle and at lower levels in brain, liver, placenta, lung, colon and spleen, DRG1 binds to TAL1 and TAL2 and is thoµght to play a role in cell proliferation and differentiation, as well as in apoptosis, sµggesting a role in tumor formation and metastasis. DRG1 is subject to polyubiquitination and sumoylation, the former of which induces proteolytic degradation. The gene encoding DRG1 maps to chromosome 22, which houses over 500 genes and is the second smallest chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DRG1 Research Areas:Cancer;Cell biology;Signal transduction