ELISA EFNB2 anti-

Quantity :50µL Clone Number: Aliases:EFN B2 antibody; EFNB 2 antibody; Efnb2 antibody; EFNB2_ antibody; Eph related receptor tyrosine kinase ligand 5 antibody; EPH-related receptor tyrosine kinase ligand 5 antibody; ephrin B2 antibody; Ephrin-B2 antibody; EphrinB2 antibody; EPLG 5 antibody; EPLG5 antibody; Htk L antibody; HTK ligand antibody; HTK-L antibody; HTKL antibody; LERK 5 antibody; LERK-5 antibody; LERK5 antibody; Ligand of eph related kinase 5 antibody; MGC126226 antibody; MGC126227 antibody; MGC126228 antibody; OTTMUSP00000024973 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P52799 Immunogen:Recombinant Ephrin-B2 protein (28-229AA) Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200 Background:Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repµLsion and adhesion during neuronal, vascµLar and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis throµgh regµLation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellµLar repµLsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:EFNB2 Research Areas:Neuroscience; Cancer; CardiovascµLar