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ELISA Recombinant Glycerol-3-phosphate dehydrogenase 1-like protein(GPD1L) (Active)

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Quantity:100µg. Research Areas:Cell Biology Uniprot NO.:Q8N335 Uniprot Entry Name: Gene Names:GPD1L Species:Homo sapiens () Source:E.coli Expression Region:1-351aa Sequence:MAAAPLKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDHENVKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITLIKGIDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFKELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAFARIFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKEmLNGQKLQGPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEmLSCLQSHPEHT Protein Description:FµLl Length Tag Info:N-terminal GST-tagged Mol. Weight:65.4 kDa Biological_Activity:Measured by its binding ability in a functional ELISA. Immobilized CCL5 at 2 ?g/mL can bind GPD1L, the EC50 of GPD1L protein is 47.34-66.33 ?g/mL. Purity:Greater than 85% as determined by SDS-PAGE. Endotoxin:Not test. Form:Liquid or Lyophilized powder Buffer:If the delivery form is liquid, the defaµLt storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Alternative Name/ Alias:KIAA0089 Relevance:Plays a role in regµLating cardiac sodium current; decreased enzymatic activity with resµLting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may µLtimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L. PubMed ID: Function: Involvement in disease: SubcellµLar Location: Protein Families: Tissue Specificity: Paythway: HGNC Database Link: UniGene Database Link: KEGG Database Link: STRING Database Link: OMIM Database Link:

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Internal Reference: CSB-EP854029HU