ELISA Recombinant Guanylate cyclase soluble subunit alpha-2(GUCY1A2),partial

Quantity:100µg. Other Quantitys are also available. For further information, please contact us. Research Areas:Signal Transduction Uniprot ID:P33402 Gene Names:GUCY1A2 Organism:Homo sapiens () AA Sequence:GDVAQQLWQGQQVQARKFDDVTmLFSDIVGFTAICAQCTPMQVISmLNELYTRFDHQCGFLDIYKVETIGDAYCVAAGLHRKSLCHAKPIALMALKMMELSEEVLTPDGRPIQMRIGIHSGSVLAGVVGVRMPRYCLFGNNVTLASKFESGSHPRRINVSPTTYQLLKREESFTFIPRSREELPDNFPKEIPGICYFLEVRTGPKPPKPSLSSSRIKKVSYNIGTMFLRETSL Expression Region:500-732aa Sequence Info:Partial Source:E.coli Tag Info:N-terminal 6xHis-tagged MW:27.8 kDa Alternative Name(s):GCS-alpha-2 Relevance:Has guanylyl cyclase on binding to the beta-1 subunit. Isoform 2 acts as a negative regµLator of guanylyl cyclase activity as it forms non-functional heterodimers with the beta subunits. Reference:"Interaction proteome of Hippo signaling: modµLar control of the co-activator YAP1." Hauri S., Wepf A., van Drogen A., Varjosalo M., Tapon N., Aebersold R., Gstaiger M. Mol Syst Biol 9:713-713(2013) Purity:Greater than 85% as determined by SDS-PAGE. Form:Liquid or Lyophilized powder Buffer:If the delivery form is liquid, the defaµLt storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20?/-80?. The shelf life of lyophilized form is 12 months at -20?/-80?. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Function: Involvement in disease: SubcellµLar Location: Protein Families: Tissue Specificity: Paythway: HGNC Database Link: UniGene Database Link: KEGG Database Link: STRING Database Link: OMIM Database Link: Lead Time Guidance:3-7 business days