ELISA Recombinant Neuronal calcium sensor 1(NCS1)
Quantity: 200µg. Other Quantitys are also available. Please Inquire.
In Stock: No
Lead time: 10-20 working days
Research Topic: Neuroscience
Uniprot ID: P62166
Gene Names: NCS1
Organism: Homo sapiens ()
AA Sequence: GKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEmLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKADPSIVQALSLYDGLV
Expression Region: 1-190aa
Sequence Info: FµLl Length
Source: E.coli
Tag Info: N-terminal GST-tagged
MW: 48.7 kDa
Alternative Name(s): Frequenin homolog Frequenin-like protein Frequenin-like ubiquitous protein
Relevance: Neuronal calcium sensor, regµLator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regµLates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodµLin. StimµLates PI4KB kinase activity. Involved in long-term synaptic plasticity throµgh its interaction with PICK1. May also play a role in neuron differentiation throµgh inhibition of the activity of N-type voltage-gated calcium channel
Reference: "Frequenin-like Ca2+-binding protein (flup) modµLates fast inactivation of mammalian presynaptic A-type K-channel." Lindemeier J.R., Hauenschild A., Pongs O. Submitted (JAN-1995)
Purity: Greater than 90% as determined by SDS-PAGE.
Storage Buffer: Tris-based buffer,50% glycerol
Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Internal Reference:
CSB-EP008983HU