ELISA Recombinant Interleukin-19 protein(IL19) (Active)

Quantity:100µg. Research Areas:Immunology Uniprot NO.:Q9UHD0 Uniprot Entry Name:IL19_ Gene Names:IL19,ZMDA1 Species:Homo sapiens () Source:E.Coli Expression Region:25-177aa Sequence:LRRCLISTDM HHIEESFQEI KRAIQAKDTF PNVTILSTLE TLQIIKPLDV CCVTKNLLAF YVDRVFKDHQ EPNPKILRKI SSIANSFLYM QKTLRQCQEQ RQCHCRQEAT NATRVIHDNY DQLEVHAAAI KSLGELDVFL AWINKNHEVM SSA Protein Description:Partial of AF192498 Tag Info:Tag-Free Mol. Weight:17.9 kDa Biological_Activity:FµLly biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using IL-20R? and IL-20R? co-transfected murine BaF3 pro-B cells is less than 1.5 ng/mL, corresponding to a specific activity of ? 6.7×105 IU/mg. Purity:>95% as determined by SDS-PAGE and HPLC. Endotoxin:Less than 1.0 EU/µg as determined by LAL method. Form:Lyophilized powder Buffer:Lyophilized from a 0.2 µm filtered PBS, pH 7.4 Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Alternative Name/ Alias:IL-19, NG.1 Relevance:May play some important roles in inflammatory responses. Up-regµLates IL-6 and TNF-alpha and induces apoptosis (By similarity). {ECO:0000250}. PubMed ID:11196675; 12370360; 19906316; 16710414; 15340161; 12403790 Function:May play some important roles in inflammatory responses. Up-regµLates IL-6 and TNF-alpha and induces apoptosis (By similarity). Involvement in disease: SubcellµLar Location:Secreted Protein Families:IL-10 family Tissue Specificity: Paythway:Jak-STATsignalingpathway HGNC Database Link:https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:5990 UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=661017 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?hsa:29949 STRING Database Link:https://string-db.org/network/9606.ENSP00000343000 OMIM Database Link:https://www.omim.org/entry/605687605687605687