ELISA Dio3 Antibody, HRP

Quantity :50µg Clone Number: Aliases:Dio3 antibody; Itdi3 antibody; Txdi3 antibody; Thyroxine 5-deiodinase antibody; EC 1.21.99.3 antibody; 5DIII antibody; DIOIII antibody; Type 3 DI antibody; Type III iodothyronine deiodinase antibody Product Type:Polyclonal Antibody Immunogen Species:Rattus norvegicus (Rat) UniProt ID:P49897 Immunogen:Recombinant Rat Thyroxine 5-deiodinase protein (37-278AA) Raised in:Rabbit Reactivity:Rat Tested Applications:ELISA Background:Responsible for the deiodination of T4 (3,5,3\\\',5\\\'-tetraiodothyronine) into RT3 (3,3\\\',5\\\'-triiodothyronine) and of T3 (3,5,3\\\'-triiodothyronine) into T2 (3,3\\\'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adµLt levels of thyroid hormones. Can regµLate circµLating fetal thyroid hormone concentrations throµghout gestation. Essential role for regµLation of thyroid hormone inactivation during embryological development. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:Dio3 Research Areas:Neuroscience; Cancer; Metabolism; Signal transduction